منابع مشابه
Acetanilide oxidation in phenylbutazone-associated hypoplastic anaemia.
Acetanilide like phenylbutazone is paraoxidized by the liver endoplasmic reticulum as a primary biotransformation step. Both compounds were given at different times to each of 10 healthy volunteer subjects and the plasma disappearances measured. Correlation was shown between plasma clearance values of the two compounds (r = + 0.7067; P < 0.05).Eight patients with hypoplastic anaemia after pheny...
متن کاملThe fate of acetanilide in man.
Therapeutic agents, in general, undergo chemical alteration in the body to form derivatives of the parent compound. Isolation and pharmacological assay of the various transformation products may yield valuable information in the Senrch for better therapeutic agents, in studies on the mechanism of drug action :,*d in the elucidation of norm+l metabolic processes. The therapeutic effect of a drug...
متن کاملBiodegradation of Para Amino Acetanilide by Halomonas sp. TBZ3
BACKGROUND Aromatic compounds are known as a group of highly persistent environmental pollutants. Halomonas sp. TBZ3 was isolated from the highly salty Urmia Lake of Iran. In this study, characterization of a new Halomonas isolate called Halomonas sp. TBZ3 and its employment for biodegradation of para-amino acetanilide (PAA), as an aromatic environmental pollutant, is described. OBJECTIVES Th...
متن کاملFemtosecond study of self-trapped vibrational excitons in crystalline acetanilide.
Femtosecond IR spectroscopy of delocalized NH excitations of crystalline acetanilide confirms that self-trapping in hydrogen-bonded peptide units exists and does stabilize the excitation. Two phonons with frequencies of 48 and 76 cm (-1) are identified as the major degrees of freedom that mediate self-trapping. After selective excitation of the free exciton, self-trapping occurs within a few 10...
متن کاملAmino acid substitution in an amidase produced by an acetanilide-utilizing mutant of Pseudomonas aeruginosa.
Mutants of Pseudomonas aeruginosa were isolated which grew with acetanilide (N-phenylacetamide) as the sole carbon source for growth. The mutants could also use acetanilide as a nitrogen source but grew better in the presence of ammonium salts. The acetanilide-utilizing mutants produced amidases which differed in substrate specificity and electrophoretic mobility from the wild-type A amidase an...
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ژورنال
عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan
سال: 1992
ISSN: 0037-9980,1883-6526
DOI: 10.5059/yukigoseikyokaishi.50.172